2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. DNA Stain

DNA Stain

DNA Stain

Related Products

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There are several different stains that can be used to visualize and photograph DNA after separation by gel electrophoresis. Molecules of the dye adhere to DNA strands and fluoresce under UV light, showing where the bands are within the gel.

Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA.There are three related Hoechst stains: Hoechst 33258, Hoechst 33342, and Hoechst 34580. The dyes Hoechst 33258 and Hoechst 33342 are the ones most commonly used and they have similar excitation/emission spectra.

DNA Stain Related Products (87):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D0021S
    EthD-d5 bromide
    EthD-d5 bromide is the deuterium labeled Ethidium bromide. EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
    EthD-d<sub>5</sub> bromide
  • HY-136248A
    Cyanine 3 Tyramide methyl indole
    		98.0%
    Cyanine 3 Tyramide methyl indole is a derivative of Cyanine 3 Tyramide (HY-136248). Cyanine 3 Tyramide is an orange fluorescent dye, and is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.
    Cyanine 3 Tyramide methyl indole
  • HY-151680
    TAMRA alkyne, 6-isomer
    TAMRA alkyne, 6-isomer is a linker of TAMRA.
    TAMRA alkyne, 6-isomer
  • HY-135413
    MeCY5-NHS ester
    MeCY5-NHS estera is a reactive dye. MeCY5-NHS estera can be used for the labeling of proteins and nucleic acids.
    MeCY5-NHS ester
  • HY-D1246
    Ethidium monoazide bromide
    Ethidium monoazide bromide is a DNA intercalating fluorescent dye that enters bacteria with damaged membranes. Ethidium monoazide bromide can be covalently linked to DNA by photoactivation. Ethidium monoazide bromide stains only dead cells. Ethidium monoazide (bromide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Ethidium monoazide bromide
  • HY-D1706
    AMCA-6-dUTP
    AMCA-6-dUTP can be used for enzymatic labeling of DNA/cDNA.
    AMCA-6-dUTP
  • HY-13735H
    Quinacrine acetate
    Quinacrine (Acriquine) acetate is a small molecule modulator of the cGAS-STING-TBK1 signaling pathway, possessing immune stimulatory activity. Quinacrine acetate has been explored for its potential therapeutic applications in enhancing anti-tumor immunity. Quinacrine acetate can improve the effectiveness of cancer immunotherapies by addressing the poor immunogenicity of various tumors. Quinacrine acetate also presents a promising strategy for overcoming the limitations associated with immune checkpoint inhibitors in cancer treatment.
    Quinacrine acetate
  • HY-D1722
    Tetramethylrhodamine-dUTP
    Tetramethylrhodamine-dUTP (TAMRA-dUTP) is used for end-labeling of DNA.
    Tetramethylrhodamine-dUTP
  • HY-15627A
    Hoechst 33342 analog trihydrochloride
    Hoechst 33342 analog trihydrochloride is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution. Storage: Keep away from light.
    Hoechst 33342 analog trihydrochloride
  • HY-D1409
    DMTr-4'-F-U-CED-TBDMS phosphoramidite
    DMTr-4'-F-U-CED-TBDMS phosphoramidite (DMTr-4'-F-uridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-F-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure.
    DMTr-4'-F-U-CED-TBDMS phosphoramidite
  • HY-135413A
    Sulfo-CY5-NHS ester potassium
    Sulfo-CY5-NHS ester potassium is a reactive dye and can be used for labeling protein nucleic acid.
    Sulfo-CY5-NHS ester potassium
  • HY-W110781
    Basic Blue 20
    Basic Blue 20 is a very convenient red-emitting DNA stains. Basic Blue 20 has relatively narrow excitation and emission spectra, with peaks at 633 and 677 nm, respectively. Basic Blue 20 also has a very high resistance to photobleaching.
    Basic Blue 20
  • HY-D1408
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite (DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-Me-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure.
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite
  • HY-162568
    7-tert-Butylfascaplysin
    7-tert-Butylfascaplysin (7-TB) is a derivative of Fascaplysin (HY-112328), that can be isolated from Fascaplysinopsis sp.. 7-tert-Butylfascaplysin induces replication stress, leads to toxic DNA double-strand breaks and apoptosis-like cell death, and thus exhibits cytotoxicity in cancer cells in nanomolar levels. 7-tert-Butylfascaplysin exhibits DNA intercalating activity with EC50 of 3.2 μM.
    7-tert-Butylfascaplysin
  • HY-16189
    Elliptinium acetate
    		Modulator
    Elliptinium acetate (NSC 264137) is a DNA intercalating agent that is highly cytotoxic to L1 210 cells and covalently binds to nucleic acids from L1210 cells. Elliptinium acetate can be used in cancer research, particularly in metastatic breast cancer.
    Elliptinium acetate
  • HY-W012642A
    2-Aminopurine dihydrochloride
    2-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence.
    2-Aminopurine dihydrochloride
  • HY-D1079
    EDANS sodium
    EDANS sodium is a potent fluorogenic substrates. EDANS sodium is a donor for FRET-based nucleic acid probes and protease substrates. EDANS sodium is often paired with DABCYL or DABSYL. The optimal absorbance and emission wavelengths of EDANS sodium are λabs = 336 nm and λem = 490 nm respectively.
    EDANS sodium
  • HY-D1686
    Biotin-16-UTP
    Biotin-16-UTP is an active substrate for RNA polymerase. Biotin-16-UTP can replace UTP in the in vitro transcription reaction for RNA labeling.
    Biotin-16-UTP
  • HY-D1660
    Acridine homodimer
    Acridine homodimer (NSC 219743), acridine dimer, is a fluorescence dye. Acridine homodimer emits a blue-green fluorescence when bound to DNA. Acridine homodimer has extremely high affinity for AT-rich regions of nucleic acids, can be used for chromosome banding.
    Acridine homodimer
  • HY-161164
    Tricyclic cytosine tC
    Tricyclic cytosine tC is a fluorescent base analogue that can be used as a fluorescent probe in nucleic acid-containing systems. The excitation wavelength is 385 nm and the emission wavelength is 505 nm.
    Tricyclic cytosine tC